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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
6.06
Human Site:
T614
Identified Species:
13.33
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
T614
G
G
Q
S
R
G
A
T
R
Q
K
K
T
M
K
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
L600
R
G
G
E
E
R
G
L
G
R
R
R
K
T
M
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
L617
A
A
Q
S
G
V
C
L
S
G
T
T
R
Q
K
Dog
Lupus familis
XP_546733
1387
151432
S598
G
S
Q
S
R
G
A
S
R
Q
K
K
T
M
K
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
A695
G
S
Q
S
R
G
T
A
R
Q
K
K
T
M
K
Rat
Rattus norvegicus
Q62688
1096
122754
G377
K
G
F
L
A
I
D
G
F
T
Q
Y
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
K39
W
K
K
Q
R
Y
F
K
L
Q
E
D
C
M
T
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D65
R
R
L
K
L
L
E
D
C
V
T
V
W
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
A589
N
E
P
P
P
E
K
A
Q
K
E
T
E
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S689
Q
A
K
Q
R
M
S
S
A
N
R
K
R
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
6.6
20
86.6
N.A.
80
6.6
N.A.
N.A.
0
20
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
20
93.3
N.A.
80
20
N.A.
N.A.
0
33.3
6.6
N.A.
20
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
10
0
19
19
10
0
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
10
10
10
10
0
0
0
19
0
10
0
10
% E
% Phe:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
10
% F
% Gly:
28
28
10
0
10
28
10
10
10
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
19
10
0
0
10
10
0
10
28
37
10
0
37
% K
% Leu:
0
0
10
10
10
10
0
19
10
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
37
10
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
37
19
0
0
0
0
10
37
10
0
0
10
0
% Q
% Arg:
19
10
0
0
46
10
0
0
28
10
19
10
19
0
0
% R
% Ser:
0
19
0
37
0
0
10
19
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
10
10
0
10
19
19
28
10
10
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _